Well-conducted meta-analyses can inform public health policy. They make information accessible for decision-makers, in a summary format that provides a critical overview of the evidence. Poorly performed meta-analyses can mislead decision-makers when, for example, they exclude some studies on purpose, introduce bias, alter original data,...
Antiretroviral therapy (ART) has transformed HIV infection into a chronic manageable condition and reduces the risk of onward HIV transmission. In light of this, UNAIDS published a document in May 2013 entitled: ‘Ending overly broad criminalization of HIV non-disclosure, exposure and transmission: critical scientific, medical...
Professor Joep Lange over Hiv-onderzoek: Het Amsterdam Diner is het jaarlijkse benefietgala van het bedrijfsleven voor de strijd tegen aids. De 22ste editie heeft zeker 500.000 euro opgeleverd. Dat heeft de organisatie zondag bekendgemaakt. Een groot deel van de opbrengst is bedoeld voor het onderzoek naar...
Tuberculosis is the main opportunistic infection in HIV-infected children, just as it is in HIV-infected adults. Despite this, screening for tuberculosis is not frequently done, due to the absence of adequate diagnostic tools. Combined with late access to antiretroviral therapy, these are missed opportunities in...
Many issues in the management of patients with drug-resistant tuberculosis rely on expert opinions rather than on evidence. Examples are the evaluation of the duration of infectiveness of the patients, the choice of preventive chemotherapy for contacts of patients with drug-resistant tuberculosis, the optimal duration...
HIV-related illnesses and deaths are on the decline in sub-Saharan Africa as increasing numbers of people get on and stay on antiretroviral therapy (ART). Treatment failure and drug resistance can undermine these gains. We recruited adults on ART at a rural HIV clinic in Coastal...
On behalf of the Lancet: a manifesto We would like to call on your support for a new vision of planetary health, based on collective public health action at all levels of society - personal, community, national, regional, global, and planetary. This vision is outlined in a new manifesto...
New published information reveals that intestinal worm infections rank among the most common afflictions of people living in extreme poverty. The numbers are quite astonishing.More than 800 million people are currently believed to harbor Ascaris roundworms in their gastrointestinal tract, while around 450 million people...
AIGHD Deputy Director Cate Hankins argues in Expert Review of Pharmacoeconomics & Outcomes Research that HIV pre-exposure prophylaxis or PrEP may be a workable option over short- to medium-term risky periods for people who are unable to use proven HIV prevention methods such as condoms...
Lactobacillus-dominated microbiome associated with reduced HIV/STI prevalence and reduced genital HIV viral load in African women Deviation from a Lactobacillus-dominated cervicovaginal microbiome may increase the risk of HIV and other sexually transmitted infections (STIs). However, little is known about the exact nature of these microbiological changes....