TECoARTe

Epidemiology and control of tuberculosis in the antiretroviral therapy era: towards a mathematical model for Cape Town, South Africa

Objective

This project aims to use a variety of epidemiologic methods to describe the local TB epidemic and its drivers, and to determine the potential impact of different public health interventions in Cape Town, South Africa. State-of-the-art statistical techniques will be used to perform an in-depth analysis of all TB cases in Cape Town in the last decade. These data will be used to develop and validate a mathematical model of the local TB epidemic. Projections of this model will be used to estimate the future impact of new and redesigned public health strategies for TB control.

Background

The resurgence of tuberculosis (TB) has been underway for almost 20 years, and despite increasingly implemented comprehensive control strategies, the epidemic in sub-Saharan Africa is continuing to expand. There is an urgent need to elucidate the reasons underlying the failing of TB control and to develop innovative public health approaches. This proposal aims to use a variety of epidemiologic methods to describe the local TB epidemic and its drivers, and to determine the potential impact of different public health interventions in Cape Town, South Africa. State-of-the-art statistical techniques will be used to perform an in-depth analysis of all TB cases in Cape Town in the last decade. These data will be used to develop and validate a mathematical model of the local TB epidemic. Projections of this model will be used to estimate the future

impact of new and redesigned public health strategies for TB control.

Summary

Name: TECoARTe
Status: Start: March, 2014
End: February, 2017
Principal Investigator: Prof. Frank G.J. Cobelens (f.cobelens@aighd.org)
Departments(s): AIGHD
Partners: Desmond Tutu HIV Centre at the University of Cape Town

Centre for Infectious Diseases Epidemiology Research (CIDER) at the Faculty

of Public Health and Family Medicine, University of Cape Town

Institute of Social and Preventative Medicine (ISPM) at the University of Bern

Contact information: Dr. Sabine Hermans (s.hermans@aighd.org)

Wiesje Zikkenheiner (w.zikkenheiner@aighd.org

Duration: 36 Months
Funded by: European Commission
Countries: Cape Town, South Africa

Amsterdam, the Netherlands

Publications: